Searchable abstracts of presentations at key conferences in endocrinology

ea0081p90 | Diabetes, Obesity, Metabolism and Nutrition | ECE2022

Evening chronotype is associated with hormonal and metabolic disorders in Polycystic Ovary Syndrome

Verde Ludovica , Barrea Luigi , Vetrani Claudia , Docimo Annamaria , De Alteriis Giulia , Savastano Silvia , Colao Annamaria , Muscogiuri Giovanna

Objective: Polycystic ovary syndrome (PCOS) is the most common female endocrine disorder. Recently in the context of obesity, which often coexists with PCOS, it has been highlighted the role of chronotype as risk factor for obesity-related cardiometabolic complications. Given the importance of chronotype categories in the context of metabolic diseases and being PCOS characterized by metabolic derangements, we aimed to investigate the prevalence of chronotype categories in wome...

ea0099oc6.4 | Oral Communications 6: Environmental Endocrinology | ECE2024

1,25-Dihydroxyvitamin D3 reduces adipogenesis and mitigates the bisphenol-A-induced pro-adipogenic effect in mouse 3T3-L1 cell line and human adipose-derived mesenchymal stem cells through miR-27-3p regulation

Provvisiero Donatella , Negri Mariarosaria , Amatrudo Feliciana , Patalano Roberta , Monto Tatiana , Pugliese Gabriella , de Alteriis Giulia , Graziadio Chiara , Colao Annamaria , Pivonello Rosario , Savastano Silvia , Pivonello Claudia

Endocrine-disrupting chemicals, including bisphenol A (BPA) may promote obesity. The role of 1,25-Dihydroxyvitamin D3 (VitD) in counteracting adipogenesis is still a matter of question. Thus, the current study aims to investigate whether and how VitD exposure during adipogenesis could prevent the BPA pro-adipogenic effect in adipocyte models: the mouse pre-adipocytes 3T3-L1 and the human adipose-derived mesenchymal stem cells (hAMSC). 3T3-L1 and hAMSC were treated with VitD (1...